Stereo-seq Large Chip Designs

STOmics Stereo-seq Large Chip Designs bring a new era of spatial transcriptomics, combining centimetre-scale field of view with true nanoscale resolution. Designed for fresh-frozen samples from any species, these large chips allow unbiased, in situ capture of the whole transcriptome across entire tissue sections.

Profile multiple organs or co-embedded tissues in parallel with high throughput and scalability, while precisely identifying individual cell types. From tissue preparation to comprehensive data analysis, Stereo-seq Large Chip Designs deliver an end-to-end solution that transforms how researchers explore spatial biology, developmental processes, and disease mechanisms.

Product Specification

Catalog Number Set Name Specifications Version Description
111SP11124-CG Stereo-seq Permeabilization Set (1cm × 2cm) 4 RXN V1.1 For determining permeabilization parameters to optimize mRNA capture
111ST13122-CG Stereo-seq Transcriptomics Set (1cm × 2cm) 2 RXN V1.3 For generating a spatially-resolved 3' mRNA library from biological tissue sections
111SP11224-CG Stereo-seq Permeabilization Set (2cm × 2cm) 4 RXN V1.1 For determining permeabilization parameters to optimize mRNA capture
111ST13221-CG Stereo-seq Transcriptomics Set (2cm × 2cm) 1 RXN V1.3 For generating a spatially-resolved 3' mRNA library from biological tissue sections
111SP11234-CG Stereo-seq Permeabilization Set (2cm × 3cm) 4 RXN V1.1 For determining permeabilization parameters to optimize mRNA capture
111ST13231-CG Stereo-seq Transcriptomics Set (2cm × 3cm) 1 RXN V1.3 For generating a spatially-resolved 3' mRNA library from biological tissue sections
111KL11160-CG Stereo-seq 16 Barcode Library Preparation Kit 16 RXN V1.1 Designed for library preparation of samples using Stereo-seq technology, enables the addition of sample barcodes and library construction.

Workflow

End-to-End Spatial Biology: From Sample to Discovery

New Stereo-seq Transcriptomics LCD FF V1.3 workflow

This end-to-end workflow combines high-resolution spatial transcriptomics with Stereo-seq, precise tissue imaging with Go Optical, robust library preparation and conversion powered by DNBSEQ™ technology, and high-throughput sequencing on the DNBSEQ platform. Compatible with both fresh-frozen (FF) and formalin-fixed paraffin-embedded (FFPE) tissue samples, it is paired with intuitive data visualization in StereoMap to enable exploration of spatial gene expression with unprecedented scale and precision.

Product Highlights

Broad Capturing Area

  • Larger chip sizes (up to 2 cm × 3 cm) enable expansive tissue coverage without losing capture efficiency, letting you study entire sections in one experiment.

Species-Agnostic

  • Compatible with fresh-frozen samples from any species, giving you flexibility to profile diverse tissue types across research models.

High-Throughput & Scalable

  • Profile multiple co-embedded tissue sections in parallel, increasing experimental efficiency while maintaining high-resolution spatial data.

Whole Transcriptome Profiling

  • Unbiased in situ capture of the entire transcriptome at nanoscale resolution delivers comprehensive spatial gene expression across tissues.

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